Transient Elastographic Values of Healthy Volunteers in a Tertiary Care Hospital

  • Bhupendra Kumar Basnet Department of Medicine NAMS, Bir Hospital, Kathmandu
  • Sudhamshu KC Department of Medicine
  • Dilip Sharma Department of Medicine
  • Dinesh Shrestha Department of Medicine

Abstract

Introduction:Transient elastography is a very promising non invasive procedure to determine liver stiffness for diagnosis of fibrosis in various chronic liver diseases. However, studies on normal values of liver stiffness in apparently healthy subjects are still few. We aimed to determine liver stiffness values in healthy Nepalese volunteers.

Methods:Transient elastography (FibroScanR, Echosens, Paris, France) was performed to find out liver stiffness values in 45 apparently healthy volunteers after explaining study protocol. Complete medical examination with routine laboratory tests was performed. Subjects with normal liver biochemistries and normal liver ultrasonography were taken for analysis.

Results:Mean liver stiffness value of study subjects was 4.24±0.70 kPa. Liver stiffness value was found higher in males than in females (4.32±0.74 vs 4.07±0.61 kPa, respectively, P=0.26) but not statistically significant. Similarly, comparison between age and liver stiffness also showed positive correlation (r=0.211) but not statistically significant (P=0.164)

Conclusions: Our study showed that the mean liver stiffness value was 4.24±0.70 kPa in our population and influence of age, gender and body mass index were not significant.

Keywords: chronic liver disease; FibroScanR; healthy volunteers; liver stiffness valve; transient elastography.

Author Biographies

Bhupendra Kumar Basnet, Department of Medicine NAMS, Bir Hospital, Kathmandu

Department of Medicine
NAMS, Bir Hospital, Kathmandu

Sudhamshu KC, Department of Medicine
Department of Medicine
Dilip Sharma, Department of Medicine
Department of Medicine
Dinesh Shrestha, Department of Medicine
Department of Medicine

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Published
2014-03-31
How to Cite
Basnet, B., KC, S., Sharma, D., & Shrestha, D. (2014). Transient Elastographic Values of Healthy Volunteers in a Tertiary Care Hospital. Journal of Nepal Medical Association, 52(193), 661-667. https://doi.org/10.31729/jnma.2189
Section
Original Article