Maxillary Calcifying Epithelial Odontogenic Tumour
The calcifying epithelial odontogenic tumor is a benign, locally invasive, slow-growing neoplasm occurring as intraosseous (94%) and extraosseous (6%) variants and with a frequency of 1-2%. Extraosseous variant is diagnosed slightly earlier than the intraosseous type. The intraosseous CEOT shows a maxilla:mandible site ratio of 1:2 and are mainly located in the premolar/molar region. Histologically, the CEOT is characterized by the occurrence of sheets, nests and masses of polyhedral, eosinophilic epithelial cells which may show cellular abnormalities including giant cell formation and nuclear pleomorphism. Some cells increase in size andproducea homogeneous, eosinophilic, 'amyloid-like' substance which may become calcified and which may be liberated as the cells break down. Enucleation with amarginof macroscopically normal tissue is the recommended treatment for CEOT involving the mandible. Maxillary CEOT are treated more aggressively, as they tend to grow more rapidly and do not usually remain well confined.
Keywords: calcifying epithelial odontogenictumor; Pindborgtumor;hemimandibulectomy. | PubMed
Pathol Microbiol Scand.1955;7:111.
2. 11. Pindborg JJ. A calcifying epithelial odontogenictumor. Cancer
3. 6. Patiño B, Fernández-Alba J, Garcia-Rozado A, Martin R,
López-Cedrún JL, Sanromán B. Calcifying epithelial odontogenic
(pindborg) tumour: A series of 4 distinctive cases and a review of
the literature. J Oral Maxillofac Surg. 2005;63:1361–8.
4. Maiorano E, Renne G, Tradati N, Viale G. Cytogical features of
calcifying epithelial odontogenictumor (Pindborgtumor) with
abundant cementum-like material. Virchows Arch. 2003;442
5. El-Labban NG. Cementum-like material in a case of
Pindborgtumor. J Oral Pathol Med. 1990;19:166–9.
6. 9. Hicks MJ, Flaitz CM, Wong ME, McDaniel RK, Cagle PT. Clear
cell variant of calcifying epithelial odontogenictumor: Case report
and review of the literature. Head Neck.1994;16:272–7.
7. Aviel-Ronen S, Liokumovich P, Rahima D, Polak-Charcon S,
Goldberg I, Horowitz A. The amyloid deposit in calcifying epithelial
odontogenictumor is immunoreactive for cytokeratins. Arch Pathol
Lab Med. 2000;124:872–6.
8. Krolls SO, Pindborg JJ. Calcifying epithelial odontogenictumor.A
survey of 23 cases and discussion of histomorphologic
variations. Arch Pathol. 1974;98:206–10.
9. Aufdermaur M. Pindborg tumour. J Cancer Res
10. Takata T, Ogawa I, Miyauchi M, Ijuhin N, Nikai H, Fujita M.
Non-calcifying Pindborgtumor with Langerhans cells. J Oral
Pathol Med. 1993;22:378–83.
11. Hafian H, Mauprivez C, Furon V, Pluot M, Lefevre B. Pindborg
tumour: A poorly differentiated form without calcification. Rev
Bouckaert MM, Roubenheimer EJ, Jacobs FJ. Calcifying epithelial
odontogenictumor with intracranial extension: Report of a case
and review of literature. Oral Surg Oral Med Oral Pathol Oral
13. Philipsen HP, Reichart PA. Calcifying epithelial odontogenictumor:
Biological profile based on 181 cases from the literature. Oral
14. Chomette G, Auriol M, Guilbert F. Histoenzymological
and ultrastructural study of a bifocal calcifying epithelial
odontogenictumor: Characteristics of epithelial cells and
histogenesis of amyloid-like material. Virchows Arch A PatholAnat
15. Goldenberg D, Sciubba J, Koch W, Tufano RP. Malignant
odontogenictumors: A 22-year experience. Laryngoscope. 2004;1
16. Cicconetti A, Tallarico M, Bartoli A, Ripari A, Maggiani F.
Calcifying epithelial odontogenic (Pindborg) tumor: A clinical
case. Minerva Stomatol. 2004;53:379–87.
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