@article{Regmi_Shrestha_KC_Jaishi_Karki_Khadka_Khadka_2017, title={Prevalence of Hepatitis D Among Patients with Hepatitis B Viral Infection Attending a Tertiary Care Centre of Nepal}, volume={56}, url={http://www.jnma.com.np/jnma/index.php/jnma/article/view/3378}, DOI={10.31729/jnma.3378}, abstractNote={<p class="p1"><span class="s1"><strong>Introduction: </strong></span>Worldwide there is variation in prevalence of Hepatitis D viral infection. Superinfection and co infection with hepatitis B viral infection is known to occur in 15-20 million people.</p> <p class="p1"><span class="s1"><strong>Methods: </strong></span>This was a descriptive cross-sectional hospital based study carried out in NAMS, Bir hospital, Kathmandu, Nepal from period of January 2017 to June 2017. Consecutive patients of chronic hepatitis B viral infection of HBsAg positive with more than two-time upper normal limit of ALT were enrolled and tested for HDV IgG.</p> <p class="p1"><span class="s1"><strong>Results:</strong></span> Forty patients were enrolled during study period. Mean age was 30.9±12.2 years. Males were 28 (70%) and females 12 (30%). Most of the patients were asymptomatic for HBV infection 32 (80%). HBeAg negative chronic hepatitis was most commonly present in 31 (77.5%). Family history of Hepatitis B viral infection was seen in 7 (17.5%) and sexual promiscuity in 5 (12.5%) as the mode of acquisition of hepatitis B viral infection. HBcIgM was positive in three patients with mean HBV DNA of 4.97x10<sup>5</sup>±4.5x10<sup>5 </sup>IU/ml in HBeAg positive group. HDV IgG was negative in all patients.</p> <p class="p1"><span class="s1"><strong>Conclusions:</strong></span> Coinfection and superinfection of hepatitis D virus were found to be uncommon at Bir hospital, Nepal.</p> <p class="p2"><span class="s2"><strong>Keywords:</strong></span><em> HbsAg; HDV DNA; HDV IgG; Hepatitis B; Hepatitis D. </em></p>}, number={208}, journal={Journal of Nepal Medical Association}, author={Regmi, Kiran and Shrestha, Jeetndra Kaji and KC, Sudhamshu and Jaishi, Bikash and Karki, Niyanta and Khadka, Dipendra and Khadka, Sandip}, year={2017}, month={Dec.}, pages={417–20} }