Reye Syndrome – A Case Report with Review of Literature .

Abstract

Here we describe a case of Reye syndrome diagnosed at postmortem liver biopsy of a three-year old
girl who presented with vomiting, low grade fever for three days and loss of consciousness for 18
hours. Clinically, the differential diagnoses were meningitis, encephalitis and septicemia. No history
of past illness or any drug ingestion including aspirin were present. Laboratory investigations
indicated a diagnosis of Reye syndrome. The child was given supportive treatment but died after
two days of admission and postmortem needle-biopsy of the liver showed microvesicular steatosis
consistent with Reye syndrome.
Key words: Microvesicular steatosis, mitochondrial hepatopathy, Reye syndrome, Reye-like syndrome