Kikuchi- Fujimoto Disease of Mesenteric Lymph Nodes Mimicking Acute Appendicitis

  • Anne Shrestha Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL.
  • Katie Newton Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL
  • Emyr Benbow Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL
  • Rajeev Kushwaha Department of Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL

Abstract

Kikuchi-Fujimoto disease, or histiocytic necrotising lymphadenopathy of unknown aetiology, is a rare, benign and self-limiting cause of lymphadenopathy often involving the cervical nodes, and rarely presenting with mesenteric lymphadenopathy. We present a 26-year-old Caucasian male, who presented with right iliac fossa pain and low grade pyrexia, mimicking acute appendicitis. He underwent a laparatomy and an extended right hemi-colectomy for a caecal mass. Histology of the specimen showed lymph nodes with extensive areas of necrosis, with abnormal architecture suggesting Kikuchi-Fujimoto lymphadenopathy. This was further confirmed by immunohistochemistry. In this context maintenance of a high index of suspicion of this condition can avoid major surgical interventions. We describe the management of our case of Kikuchi-Fujimoto’s disease involving the mesenteric nodes and provide an up to date review of the pertinent literature on this subject. 

Keywords: abdominal mass; Kikuchi- Fujimoto disease; mesenteric lymphadenopathy; necrotising lymphadenitis.

 

Published
2013-12-31
How to Cite
Shrestha, A., Newton, K., Benbow, E., & Kushwaha, R. (2013). Kikuchi- Fujimoto Disease of Mesenteric Lymph Nodes Mimicking Acute Appendicitis. Journal of Nepal Medical Association, 52(192). https://doi.org/10.31729/jnma.2440
Section
Case Reports