Comparative study of epidural administration of 10 ml of 0.1% bupivacaine with 2 mg butorphanol and 10 ml of 0.25% plain bupivacaine for analgesia during labor

Abstract

Analgesia during labor provided by two epidural drug regimens was compared in a double blind,
randomized, prospective study. Group A (n = 12) received 10 ml bolus doses of 0.1% bupivacaine
with butorphanol 2 mg while Group B (n = 8) received 10 ml of 0.25% plain bupivacaine. The
objectives of this study was to compare, between the quality of an epidural labor analgesia using
initial loading dose of 0.1% bupivacaine and 2 mg butorphanol with a initial loading dose of 0.25%
bupivacaine. In Group A, incidence of motor block was 8.3% and that of prolong 2nd stage of labor
was 16.7%, both were decreased in comparison with Group B, although they were not statistically
significant. Hemodynamic variables were stable and no adverse neonatal and maternal outcome
was observed in both groups. Addition of butorphanol to bupivacaine may be safe alternative to
reduce motor block and decrease prolong 2nd stage for epidural labor analgesia.
COmpaRatIve StUDy Of epIDURal aDmINIStRatION Of 10 ml Of
0.1% bUpIvaCaINe wIth 2 mg bUtORphaNOl aND 10 ml Of 0.25%
plaIN bUpIvaCaINe fOR aNalgeSIa DURINg labOR

Key Words: Labor analgesia, epidural analgesia, local anesthetic bupivacaine, butorphanol.