Burden of Alcoholic Liver Disease in a Tertiary Care Center: A Descriptive Cross-sectional Study

  • Shikha Rizal Department of Biochemistry, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal
  • Bishal Raj Joshi Department of Biochemistry, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal
  • Arambam Giridhari Singh Department of Biochemistry, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal
Keywords: alanine transaminase; alcoholic liver disease; aspartate transaminase; de-ritis ratio; gamma glutamyltransferase.

Abstract

Introduction: Alcoholic liver disease is a serious health problem related to an unhealthy lifestyle. The three most widely recognized forms of alcoholic liver disease are alcoholic fatty liver, acute alcoholic hepatitis, and alcoholic cirrhosis. The main aim of our study is to find out the prevalence of alcoholic liver disease in tertiary care center.

Methods: A descriptive cross-sectional study was conducted among inpatient cases admitted in the medicine department of tertiary care center from 1st June 2018 to 31st May 2019. Ethical approval was taken for the study. Convenience sampling method was used. All the biochemical parameters were expressed as mean±standard deviation for each group and point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

Results: Prevalence of alcoholic liver disease is 50 (50%) at a 95% Confidence Interval (40.2%-59.8%) and non-alcoholic fatty liver disease is also the same. The mean age of alcoholic liver disease was 59±12 years where as the mean age for non-alcoholic fatty liver disease was 46±18 years. Out of fifty patients of alcoholic liver disease, majority 48 (96%) of the cases were males which suggests that the prevalence of alcoholic liver disease is very common in males. Similarly, for non-alcoholic fatty liver disease, prevalence was 34 (68%) showing higher prevalence than that of females.

Conclusions: Prevalence of alcoholic liver disease is low compared to previous studies done in the similar settings. Monitoring these biochemical parameters in alcoholic liver disease at early stage could guide in planning the protocol for the initial treatment.

Published
2019-10-31
How to Cite
Rizal, S., Raj Joshi, B., & Giridhari Singh, A. (2019). Burden of Alcoholic Liver Disease in a Tertiary Care Center: A Descriptive Cross-sectional Study . Journal of Nepal Medical Association, 57(219). https://doi.org/10.31729/jnma.4631
Section
Original Article