Coexistence of Cardiomyopathy and Chronic Liver Disease in Non-Moderate Drinkers

  • Mani Prasad Gautam Department of Cardiology, College of Medical Sciences, Bharatpur
  • Usha Ghimire Applied Biochemist, COMAT, Kathmandu
  • Gangapatnam Subramanyam Department of Cardiology, College of Medical Sciences, Bharatpur
  • Sogunuru Guruprasad Department of Cardiology, College of Medical Sciences, Bharatpur

Abstract

Introduction: The dose-response relationship suggests a toxic effect of alcohol on heart and liver and
the possibility of a correlation between alcohol-induced liver and heart disease. The present study
was aimed to look into the relationship between chronic liver and heart muscle disease among the
non-moderate drinkers in our context.
Methods: An observational study on non-moderate chronic drinkers was carried out. Clinical
evaluation along with detail sonographic study of heart and liver was conducted.
Results: Fifty-eight percent had echocardiographic features consistent with heart muscle disease,
either as a dilated cardiomyopathy, categorized by the presence of echo features of impaired LV
systolic function and dilated left ventricle or as a possible cardiomyopathy categorized by the
presence of any of these two echo features. Similarly, 56 of the total recruits showed ultrasonographic
evidence of chronic liver disease as cirrhosis or early cirrhosis. Approximately, 86% of these 56 non-moderate drinkers with chronic liver disease also had echocardiographic features of heart muscle
disease and 83% of the 58 non-moderate drinkers showing echo features of heart muscle disease had
ultrasonographic features of chronic liver disease.
Conclusions:Our study showed a strongly positive relationship on the coexistence of chronic liver
disease and cardiomyopathy among the non-moderate drinkers. Non-moderate drinkers with
chronic liver disease have a high likelihood of having a concurrent clinical or sub-clinical heart
muscle disease and vice versa.

Keywords: alcohol; chronic liver disease; heart muscle disease; non-moderate drinking.

Published
2013-03-31
How to Cite
Gautam, M., Ghimire, U., Subramanyam, G., & Guruprasad, S. (2013). Coexistence of Cardiomyopathy and Chronic Liver Disease in Non-Moderate Drinkers. Journal of Nepal Medical Association, 52(189), 217-223. https://doi.org/10.31729/jnma.552
Section
Original Article