Herlyn Werner Wunderlich Syndrome Presenting with Ischemic Stroke due to Suspected Paroxysmal Nocturnal Hemoglobinuria: A Case Report

Authors

  • Ayushma Acharya Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal https://orcid.org/0000-0002-4955-2397
  • Prajwala Yogi Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
  • Pramod Singh Faisalabad Medical University, Punjab, Pakistan https://orcid.org/0000-0001-6350-6293
  • Tulsi Ram Bhattarai Department of Internal Medicine, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal

DOI:

https://doi.org/10.31729/jnma.5838

Keywords:

cerebral ischemia, aroxysmal nocturnal hemoglobinuria, stroke

Abstract

Paroxysmal nocturnal hemoglobinuria can rarely present as cerebral ischemia and stroke due to arterial thrombosis. However, it should be considered in a young patient with bone marrow failure features, systemic thromboses, and hemolysis. The variants of paroxysmal nocturnal hemoglobinuria pose a diagnostic challenge and hence are important to recognize. We report a case of a 28-years-old female with Herlyn Werner Wunderlich Syndrome who presented with an ischemic cerebrovascular accident, pancytopenia, hemoglobinuria, and widespread abdominal thromboses suggestive of paroxysmal nocturnal hemoglobinuria. The patient was managed symptomatically and referred to a hematologist.

Additional Files

Published

2021-02-28

How to Cite

Acharya, A. ., Yogi, P., Singh, P. ., & Bhattarai, T. R. (2021). Herlyn Werner Wunderlich Syndrome Presenting with Ischemic Stroke due to Suspected Paroxysmal Nocturnal Hemoglobinuria: A Case Report. Journal of Nepal Medical Association, 59(234), 192–196. https://doi.org/10.31729/jnma.5838

Issue

Vol. 59 No. 234 (2021): JNMA: Published Monthly

Section

Case Reports

License

Copyright (c) 2021 Ayushma Acharya, Prajwala Yogi, Pramod Singh, Tulsi Ram Bhattarai

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