Methicillin-resistant Staphylococcus aureus in Nepal

Authors

  • Lok Bahadur Shrestha School of Medical Sciences and The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia https://orcid.org/0000-0002-0054-0715
  • Gopiram Syangtan Tribhuvan University, Shi-Gan International College of Science and Technology, Kathmandu, Nepal
  • Ajaya Basnet Tribhuvan University, Shi-Gan International College of Science and Technology, Kathmandu, Nepal
  • Krishna Prasad Acharya Animal Quarantine Office, Budhanilkantha, Kathmandu, Nepal
  • Arun Bahadur Chand Department of Clinical Laboratory, Kist Medical College & Teaching Hospital, Kathmandu, Nepal
  • Khilasa Pokhrel Department of Microbiology, Kathmandu Medical College, Sinamangal, Kathmandu, Nepal

DOI:

https://doi.org/10.31729/jnma.6251

Keywords:

clindamycin, methicillin-resistant Staphylococcus aureus, multi drug resistance

Abstract

Staphylococcus aureus is both a frequent commensal and a leading cause of endocarditis, bacteremia, osteomyelitis and skin and soft tissue infections and device-related infections. We performed this minireview to summarize the prevalence of Staphylococcus aureus among clinical samples and estimate the proportion of methicillin-resistant Staphylococcus aureus. The prevalence of Staphylococcus aureus among clinical isolates in Nepal is 34.5%. On average, the proportion of multi-drug resistance in Staphylococcus aureus is 57.1%. Methicillin-resistant Staphylococcus aureus accounts for a total of 41.7%. Inducible clindamycin resistance was detected in about 35% of the isolates. A regular antimicrobial resistance surveillance mechanism is necessary to mitigate the development of resistance among organisms and further spread of superbugs like methicillin-resistance Staphylococcus aureus.

Additional Files

Published

2021-05-25

How to Cite

Shrestha, L. B., Syangtan, G. ., Basnet, A. ., Acharya, K. P. ., Chand, A. B. ., & Pokhrel, K. . (2021). Methicillin-resistant Staphylococcus aureus in Nepal. Journal of Nepal Medical Association, 59(237), 518–522. https://doi.org/10.31729/jnma.6251

Issue

Vol. 59 No. 237 (2021): JNMA: Published Monthly

Section

Review Article

License

Copyright (c) 2021 Dr Lok Bahadur Shrestha

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