REDUCING MORTALITY FROM PERFORATED PEPTIC ULCER IN NEPAL
DOI:
https://doi.org/10.31729/jnma.710Abstract
ABSTRACT
A study was undertaken to compare mortality from perforated peptic ulcer before and after introduction of
pre-operative, intra-operative and post-operative measures to improve clinical care of patients affected by
this condition. Data was accrued prospectively over 6 months (24 patients) and compared with the previous
6 months of historical controls (27 patients). Mortality showed a trend towards improvement. (9/27 c.f. 3/
24, p=0.12 n.s., Fisher exact test). Based on these findings and changing ideas in regard to disease transmission
emerging from the recent literature, a framework for limiting mortality from perforated peptic ulcer in
Nepal is proposed.
Key Words: Perforation, peptic ulcer, Nepal, mortality reduction, Helicobacter pylori.
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