Pure red cell aplasia caused by Parvo B19 virus in a kidney transplant recipient

Authors

  • A Baral Department of Nephrology, National Academy of Medical Sciences, Bir Hospital
  • B Poudel Civil Service Hospital of Nepal, Baneswor, Kathmandu
  • R K Agrawal Department of Nephrology, National Academy of Medical Sciences, Bir Hospital
  • R Hada Department of Nephrology, National Academy of Medical Sciences, Bir Hospital
  • S Gurung Department of Nephrology, National Academy of Medical Sciences, Bir Hospital

DOI:

https://doi.org/10.31729/jnma.73

Abstract

Parvo B19 is a single stranded DNA virus, which typically has affi nity for erythroid progenitor cells in the bone marrow and produces a severe form of anemia known as pure red cell aplasia. This condition is particularly worse in immunocompromised individuals. We herein report a young Nepali male who developed severe and persistent anaemia after kidney transplantation while being on immunosuppressive therapy. His bone marrow examination revealed morphological changes of pure red cell aplasia, caused by parvovirus B19. The IgM antibody against the virus was positive and the virus was detected by polymerase chain reaction in the blood. He was managed with intravenous immunoglobulin. He responded well to the treatment and has normal hemoglobin levels three months post treatment. To the best of our knowledge, this is the fi rst such case report from Nepal.

Keywords: Intravenous immunoglobulin, kidney transplant recipient, Parvovirus B19, pure red cell aplasia.

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Published

2012-06-30

How to Cite

Baral, A., Poudel, B., Agrawal, R. K., Hada, R., & Gurung, S. (2012). Pure red cell aplasia caused by Parvo B19 virus in a kidney transplant recipient. Journal of Nepal Medical Association, 52(186). https://doi.org/10.31729/jnma.73

Issue

Vol. 52 No. 186 (2012)

Section

Case Reports

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