A rare case of virilizing adult granulosa cell tumor

Authors

  • Kaveeta Dawaka Asst. Pro. Obs. & Gyn., Manipal College of Medical Sciences Pokhara
  • A Gupta Asst. Pro. Pathology, Manipal College of Medical Sciences Pokhara
  • S Joshi Medical Officer, Western Regional Hospital Pokhara
  • S Bajpai Lecturer Obstetrics & Gynecology, Manipal College of Medical Sciences Pokhara
  • H S Basi M.B.B.S. Intern, Manipal College of Medical Sciences Pokhara

DOI:

https://doi.org/10.31729/jnma.806

Abstract

A twenty eight year old lady, married for two years with no issue, presented at Western
Regional Hospital Pokhara on 8th July, 1999 with a history of amenorrhea for 1½
years, lump abdomen 1 year, hoarseness of voice for 1 year and signs of hirsutism for
the same duration. She was taken up for laparotomy wherein a left ovariectomy with
salpingectomy was done and a large cystic ovarian tumor was removed. Post operative
period was uneventful and she was advised follow up. The histopathological diagnosis
was Adult Granulosa Cell Tumor. What made this case interesting is that most
Granulosa Cell Tumors (about 3/4th) are estrogenic or feminizing, but rare examples,
including a disproportionate number of large thin walled cystic tumors are androgenic.
This was one of those rare virilizing tumors with classical features of infertility,
amenorrhea, hoarseness of voice, clitiromegaly, and breast atrophy, but we could not
estimate testosterone levels due to lack of facilities available.

Key Words: Granulosa Cell Tumor, Virilizing Ovarian Tumors, Sex Cord stromal tumors.

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How to Cite

Dawaka, K., Gupta, A., Joshi, S., Bajpai, S., & Basi, H. S. (2013). A rare case of virilizing adult granulosa cell tumor. Journal of Nepal Medical Association, 39(136), 351–353. https://doi.org/10.31729/jnma.806

Issue

Vol. 39 No. 136 (2000)

Section

Case Reports

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