Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre

Authors

  • Subhana Thapa Karki Department of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal
  • Najala Khatun Department of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, Nepal
  • Ram Hari Chapagain Department of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, Nepal
  • Nisha Jyoti Shrestha Department of Pediatric Medicine, National Academy of Medical Sciences, Mahaboudha, Kathmandu, Nepal
  • Sumit Agrawal Department of Pediatric Medicine, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal

DOI:

https://doi.org/10.31729/jnma.8455

Keywords:

children, hypothyroidism, nephrotic syndrome, prevalence

Abstract

Introduction: Nephrotic syndrome is a glomerular disease characterized by massive urinary protein loss occurring in children. Proteinuria also leads to loss of thyroid binding globulin affecting thyroid function. This study aimed to find out the prevalence of hypothyroidism among children with nephrotic syndrome admitted to a tertiary care centre.

Methods: A descriptive cross-sectional study was conducted among children with nephrotic syndrome admitted to a tertiary care centre from 06 July 2020 to 06 June 2021 after obtaining ethical approval from the Ethical Review Committee. They were tested for free T3, free T4 and TSH. A convenience sampling method was used. The point estimate was calculated at a 90% Confidence Interval.

Results: Among 69 children with nephrotic syndrome, the prevalence of hypothyroidism was 49 (71.01%) (62.03-80.00, 90% Confidence Interval).

Conclusions: The prevalence of hypothyroidism among children with nephrotic syndrome was higher than other studies done in similar settings.

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Published

2024-02-24

How to Cite

Thapa Karki, S. ., Khatun, N. ., Chapagain, R. H. ., Shrestha, N. J. ., & Agrawal, S. . (2024). Hypothyroidism among Children with Nephrotic Syndrome Admitted to a Tertiary Care Centre. Journal of Nepal Medical Association, 62(270), 110–113. https://doi.org/10.31729/jnma.8455

Issue

Vol. 62 No. 270 (2024): JNMA: Published Monthly

Section

Original Article

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Copyright (c) 2024 Subhana Thapa Karki

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