TY - JOUR AU - Hirachand, Suspana AU - Bajracharya, Junu AU - Pradhanang, Sabi AU - Lama, Sanju PY - 2013/07/01 Y2 - 2024/03/28 TI - Detection of Abnormal Cervical Cytology in Papanicolaou Smears in a Tertiary Care Center JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 52 IS - 191 SE - Original Article DO - 10.31729/jnma.2273 UR - https://www.jnma.com.np/jnma/index.php/jnma/article/view/2273 SP - AB - <p><strong>Introduction:</strong> Cancer of uterine cervix is a leading cause of mortality and morbidity among women<br />worldwide. In developing countries it is the most common gynaecological cancer and one of the<br />leading causes of cancer death among women. Pap smears are commonly used as cytological<br />screening test for successful eradication of precancerous lesions, which has made it a routine<br />procedure worldwide.</p><p><br /><strong>Methods:</strong> This descriptive study was conducted at Kathmandu Medical College Teaching Hospital,<br />Kathmandu within a period of two years from January 2011 to December 2012. A total of 1369 cases<br />were screened.</p><p><br /><strong>Results:</strong> In this study, cytological examination of the smears showed 944 (68.95%) inflammatory<br />smears, 301(21.99%) normal smears, 101(7.38%) atrophic smears, seven (0.51%) ASCUS, two (0.15%)<br />LSIL, four (0.29%) HSIL and two (0.15%) squamous cell carcinoma. Radiation changes were seen in<br />three (0.22%) cases. Of all the smears studied five (0.36%) cases were inadequate. Regarding ethnicity,<br />incidence of epithelial cell abnormalities was high in Tamang (5 cases). Eleven cases (73.33%) of<br />epithelial cell abnormalities were seen in patients from urban areas.</p><p><br /><strong>Conclusions:</strong> In country like Nepal with predominant rural population, screening and awareness<br />programs with co-operation of media, non-government organizations and government should be<br />formulated for early detection of cervical cancer.<br />_______________________________________________________________________________________<br /><strong>Keywords:</strong> Bethesda system; cervical intraepithelial lesions; pap smear<br />___________________________________________________________________________</p> ER -