TY - JOUR AU - Kandel, Bishnu Prasad AU - Singh, Yogendra AU - Singh, Keshav Prasad AU - Khakurel, Mahesh PY - 2013/07/01 Y2 - 2024/03/28 TI - Gastric Cancer Perforation: Experience from a Tertiary Care Hospital JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 52 IS - 191 SE - Original Article DO - 10.31729/jnma.2276 UR - https://www.jnma.com.np/jnma/index.php/jnma/article/view/2276 SP - AB - <p><strong>Introduction:</strong> Gastric cancer perforation can occurs in advanced stage of the disease and is often<br />associated with a high morbidity and mortality. Peritonitis due to perforation needs emergency<br />laparotomy and different surgical procedures can be performed for definitive treatment. Surgical<br />procedures largely depend on the stage of the disease and general condition of the patient. This<br />study was carried out to evaluate the outcome and role of different surgical procedures in gastric<br />cancer perforation.</p><p><strong>Methods:</strong> Medical record of patients with gastric perforation, who were treated during ten years<br />period, was reviewed retrospectively. Data regarding clinical presentation, surgical procedures,<br />staging and survival of patients were obtained.</p><p><strong>Results:</strong> Features suggestive of diffuse peritonitis were evident in all cases. The majority of the<br />patients underwent emergency surgery except one who died during resuscitation. The majority of<br />patients were in stage III and stage IV. Surgical procedure includes simple closure and omental patch<br />in five patients, simple closure and gastrojejunostomy in nine patients, gastrectomy in six patients<br />and Devine’s antral exclusion in one patient. Surgical site infection was the most common (45.5%)<br />postoperative complication. Four patients died within one month of the surgery. Three patients who<br />underwent gastrectomy survived for one year and one patient survived for five years.</p><p><strong>Conclusions:</strong> Although gastric cancer perforation usually occurs in advanced stage of the disease,<br />curative resection should be considered as far as possible.<br />_______________________________________________________________________________________<br /><strong>Keywords:</strong> gastric cancer; gastrectomy; laparotomy; perforation; peritonitis.</p> ER -