TY - JOUR AU - Gulshan, Shazia AU - Rahman, Muhammed Jawaid AU - Sarkar, Ranu AU - Ghosh, Suman AU - Hazra, Rathin PY - 2016/12/23 Y2 - 2024/03/29 TI - An Interesting Case of Basal Cell Carcinoma with Raynaud’s Phenomenon Following Chronic Arsenic Exposure JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 55 IS - 204 SE - Case Reports DO - 10.31729/jnma.2592 UR - https://www.jnma.com.np/jnma/index.php/jnma/article/view/2592 SP - 100-102 AB - <p>Arsenic is commonly known to be associated with squamous cell carcinoma. Among the lesser known associations is basal cell carcinoma and even rarer is its effect on blood vessels causing peripheral vascular disease. Here we present a case of a 55 yr old man with ulceroproliferative lesions on scalp and forehead along with several hyperpigmented patches on trunk and extremities. He had symptoms suggestive of Raynaud’s phenomenon that eventually led to digital gangrene. FNAC was done which was suggestive of basal cell carcinoma. On further enquiry, he was found to reside in an arsenic endemic zone and was investigated for blood arsenic level which was elevated. Punch biopsy from different lesions from body confirmed nodular basal cell carcinoma. Presently the patient has stopped drinking water from the local tubewell. On follow-up he shows improvement of Raynaud’s phenomenon and&nbsp;skin&nbsp;lesions.<br><br><strong>Keywords:</strong> <em>basal cell carcinoma; chronic arsenic exposure; raynaud’s phenomenon.</em>&nbsp;|&nbsp;<strong><a title="Click Here for PubMed" href="https://www.ncbi.nlm.nih.gov/pubmed/?term= 28029677">PubMed</a></strong></p> ER -