TY - JOUR AU - Hamal, Diwa AU - Kafle, Prerna Arjyal AU - Poudyal, Prija AU - Saiju, Rohit AU - KC, Hony AU - kafle, Santosh PY - 2019/06/30 Y2 - 2024/03/29 TI - Congenital Microphthalmia with Orbital Cyst: A Case Series JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 57 IS - 217 SE - Case Reports DO - 10.31729/jnma.4473 UR - https://www.jnma.com.np/jnma/index.php/jnma/article/view/4473 SP - AB - <p>Microphthalmos results from incomplete invagination of the optic vesicle or closure of the<br>embryonic fissure. We present three patients with unilateral congenital microphthalmia with<br>cyst. None of them had vision in the affected eye since birth, with gradually increasing<br>mass encroaching towards lower fornix and lower eyelid ectropion. On examination and<br>investigations, patients had large orbital cyst with microphthalmia pushing the eyeball superiorly<br>and posteriorly in affected orbit. Microphthalmic globe with cyst was surgically excised and<br>histopathologically studied. Orbital cavity was big enough to occupy the conformer and the<br>prosthetic eye after 6 weeks. Diagnosis was confirmed by large communicating orbital cyst with<br>microphthalmia without systemic association in all the patients. None of the mothers of patients<br>had (antenatal care) ANC check up. All the parents had consanguineous marriage. ANC check<br>up with ultrasound at 14-16 weeks of pregnancy is important for genetic counselling.&nbsp;</p> ER -