TY - JOUR AU - Giri, Arun AU - Kafle, Raju AU - Singh, Ganesh Kumar` AU - Niraula, Niraj PY - 2020/01/31 Y2 - 2024/03/29 TI - Prevalence of E. Coli in Urinary Tract Infection of Children Aged 1-15 Years in A Medical College of Eastern Nepal JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 58 IS - 221 SE - Original Article DO - 10.31729/jnma.4796 UR - https://www.jnma.com.np/jnma/index.php/jnma/article/view/4796 SP - AB - <p><strong>Introduction:</strong> Urinary tract infection is one of the commonest causes of childhood morbidity. Early<br>diagnosis and appropriate choice of antimicrobials is essential. Hence, this study aims to identify the<br>prevalence of Escherichia coli in childhood urinary tract infections.</p><p><br><strong>Methods:</strong> This was a hospital based descriptive cross-sectional study conducted in Nobel Medical<br>College, Biratnagar over a period of one year. A total of 163 cases aged 1-15 years were included and<br>clinical profile, laboratory reports including bacterial isolates in urine cultures and their sensitivity<br>patterns were documented.</p><p><br><strong>Results:</strong> The prevalence of Escherichia coli is 45 (53.57%) C.I. Escherichia coli was the most common<br>organism isolated in bacterial cultures followed by Klebsiella 12 (14.29%), Enterococcus 10 (11.90%).<br>Urinary tract infection was common among females with male: female ratio of 1:2.3. Fever 152<br>(93.2%) and abdominal pain 113 (69.3%) were the most common presenting symptoms. Escherichia<br>coli was found most sensitive to Nitrofurantoin 43 (95.5%) followed by Ciprofloxacin 41 (91.1%) and<br>Amikacin 40 (88.8%).</p><p><br><strong>Conclusions:</strong> Urinary tract infections in childhood require prompt attention and treatment to prevent<br>significant morbidity and mortality. From this study it can be concluded that Escherichia coli is one<br>of the most common isolates in urine culture and Aminoglycosides and Fluoroquinolones can be<br>accepted as empirical treatment regimens for childhood Urinary tract infections.</p> ER -